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Introduction
The question, Are humans genetically
related to other living species? has been a
Subject: that has loomed in the minds of the scientific world for
centuries. The answer to this challenging question has produced
some interesting findings in the scientific laboratory. Special
laboratory experimentation has proven that humans and other living
species are genetically similar. In fact, they share a very similar
genetic coding. This seemingly genetic interrelatedness of species
has provided revolutionary discoveries in the Human Genome Project.
Today new questions are emerging. These questions
ask things like, Can science and theology be studied together?
Is there a connection between human disease and nonhumans
and disease in light of theology? Are geneticists and other
researchers morally and ethically in the right, to experiment by
manipulating the life of other species for the sake of humans? Is
there a deeper theological implication in genetics? These questions
are now at the center of major discussions between theologians and
doctors in the field of medicine.
Theologians and researchers are feeling a
tension from questions like the ones mentioned above because the
questions and answers may take them into areas not previously explored,
and where traditional value-systems have no ready-made responses.
This project aims to address some of these questions.
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Genetics and Disease
in Humans and Other Species Research Findings
Humans and other living species react similar
to genetic manipulation and experimentation. Genes that cause certain
diseases in humans are also resulting in the same or similar diseases
in nonhumans. These great strides in genetic research, has revealed
that humans and other living species are similarly affected by disease.
For example, Copper disease in Bedlington Terriers, which
eventually causes liver failure, is like Wilsons disease in
man, although it is not the same gene. It is sometimes hard to collect
large enough ancestral lineage for genetic studies in rare diseases
in human but in animals you can produce large pedigrees,
identify the genetic regions and see if these regions are also involved
in the rare conditions in man. It has also been found that
retinitis pigmentosa in men, a blindness condition, is essentially
progressive retinal atrophy in dogs.
The dog is divided into about three - hundred
breeds. There are approximately three hundred - eighty inherited
diseases that have been recognized in dogs. Many of these are exact
analogues of human disease. It has been discovered that the gene
that leads to disease is gene number nine. The study of this gene
has contributed much biological information in the study of human
and animal diseases.
In central Africa researchers have found a herpes virus in gorillas
and chimpanzees that is associated with Kaposis sarcoma in
humans. This strand of herpes had previously been identified in
other animal species, but not in great apes. The blood analysis
made on these primates in Africa revealed a herpes virus strand
found in human Kaposis sarcoma.
These results indicate that the great apes
from central Africa could provide a reservoir of new herpes viruses
that are potentially transmissible to humans. This finding further
indicates that these primates may cause persistent infection, leading
under certain circumstances to epidemic level within the human population.
And a rhesus monkey that was made from an
egg that had been modified to include a simple jellyfish gene is
a good example of laboratory experimental and manipulation. The
researchers who performed this experiment believe that this type
of technology could be used to introduce more significant changes,
such as those that would make primates to mimic closely human diseases
like breast cancer or HIV.
This could hasten understanding of disease
processes and the development of new therapies. For example, researchers
believe through experimentation that an Alzheimers gene could
accelerate the development of a vaccine for that disease. In this
way they hope to bridge the scientific gap between transgenic mice
and humans.
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Do Other Species Suffer
in Disease as Humans Suffer?
It is often necessary to use animals to understand
human diseases, some of the work on cognitive diseases, such as
schizophrenia, can only be carried out in people. Animal genetics
will increasingly help the search for human genetic diseases. The
examples cited here points out very strongly, humans and other species
both share in the suffering of similar diseases. This in fact supports
the idea of species solidarity. When one suffers all suffers. These
results also indicate a species unity involving certain diseases.
The animal studies mentioned here were found on web-site links mentioned
at the beginning of this discussion.
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Human Uniqueness
Even though science is proving that genetically
other species and humans are showing great similarities, there still
remains something in each of us that uniquely defines who we are
as an individual. This uniqueness distinguishes each of us from
each other and from other species. As humans we are able to think
rationally. We can solve complex problems. We can think abstractly.
We have the authority to affect our own destinies, in that we have
free will. While other creatures do not appear to be able to do
these complex skills to the degree that humans can, if at all.
Only identical twins come the closest to being
exactly alike. For the rest of us there are some differences in
each individual that make us who we are. This individuation of the
human species makes it impossible for one person to take another
persons place. In other words, there is something in our DNA
that makes us distinct from other individuals and other species.
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Differences in the
Research Process Between Humans and Other Species
In disease both humans and other nonhumans
suffer. The affects that disease has on humans can be studied, verbalized
and interpreted but in nonhumans we can only study the affects and
draw conclusions on their implications. As humans we are able to
discuss how diseases are affecting us while nonhumans cannot communicate
their feelings to us. Theologian Dr. Theodore Jennings of Chicago
Theological Seminary states that, Individuation is not just
a spiritual or mental reality but a biological one which
is of great consequence.
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Genetics, God and
Disease
We all have our own personal identity. However,
with the understanding of the genome of an individual, new possibilities
began to emerge. Each individual is also uniquely affected by disease,
just as other species are uniquely affected by disease. God created
all living things in creation. All living creatures react to sickness
and disease.
Humankind shares their world with other living
things therefore we are all affected by what happens within our
world just because we are in it together. This means that disease
is apart of all living things, and will affect all livings things
individually and collectively. Thus, disease is universal.
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Theology, Ethics
and Science
When looking at this discussion on the affects
of genetics and disease in humans and other species, we must also
take into consideration the theological, ethical, social and moral
issues. For generations theologians and scientists have argued that
the biological sciences and theology have no reasonable relationship
between them. The study of the affects of disease on humans and
nonhumans would never in past generations have been a topic of discussion
in a theology class or a scientific laboratory. How can the image
of God be explained in genetics and disease in both humans and other
living species?
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Human Creation
and the Image of God
Humans are reflections of Gods glory.
Our reason, creativity, speech, and self-determination are the image
of God. It is our entire self that reflects the image of God. Knowing
that we are made in Gods image and thus share many of His
characteristics provides a solid basis of self worth. While, humans
are made in the image of God we cannot devalue other living creatures.
They too were made by God, who Himself said, while in the Garden
of Eden, That everything He made was good.
The Creation story tells us that God placed
value on everything that He made. He then gave man total authority
over all of His creation. Does that mean, however, that man has
the power to manipulate those things that are pertaining to disease
or life and death issues? If God made all things and they were good,
then where does sickness and disease originate?
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The Genetic
Origin of Disease
Science is now
providing us an answer to this question. Through scientific genetic
research it has been proven that disease results from genetic mutations.
This means that something triggers a particular gene to over produce
itself. From this triggering the mutated gene is unable to reverse
itself, to produce at its right level.
However, many diseases
that appear in humans have been passed down through the genes of
ancestors. Much of the research of the past believed that disease,
at least for humans was environmental, occupational or deficient
diets. We might be able to better understand the diseases found
in other species by examining their genetic make-up.
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Disease
Prevention and the Scientific Researcher
Scientific research has
helped to play major roles in studying, curing and preventing many
diseases. According to D. Gareth Jones in his book The Brave
New People, this research has placed researchers on a status
of being known as gods. From this unpopular label many scientist
have begun to understand that they are still human beings working
within a specific social, political and religious context. From
this context there is another consideration to be expressed, and
that is in reference to how scientific research has affected other
living species. Much of the research findings come from the experimentation
on laboratory animals.
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All Living
Creatures Living Together
Science therefore, besides
altering the physical world, also introduces moral situations that
have no obvious answers. It affects us as human beings in
relationship to the environment, to other living species, and to
God. This highly complex relationship with other species has socio-cultural
implications and has been handed down to us historically through
a series of ideal and normative descriptions as well as in myths.
Since, other living creatures
also live in Gods creation, we as humans must respect their
rights to live in harmony with their own kind, and also with us.
Their right to share in Gods creation and live unthreatened
is the context from which we must approach disturbing their environment
for scientific purposes
For this reason, we can
state that the man-animal relationship has been the object of ethical
discussions. There is also present a constant concern for tradition
which places at the center of consideration the solidarity between
man and animal based on the common reality of suffering pain and
disease.
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No More Moral
Neutrality!
The experimentation and
manipulation of genes and mutations in the scientific laboratory,
by the scientists can no longer claim moral neutrality in their
investigations. The pain suffered by animals when certain operations
are performed upon them has to be looked at for their implications.
Do scientist have the right to inflict pain upon animals for the
sake of furthering science? Are these scientists in effect stepping
beyond their boundaries into the realm of disturbing Gods
creation?
These questions have now
forced theologians and scientist to enter into dialogue about the
moral, ethical and religious implications. In this discussion we
must begin with the conviction that the world is a continuous creation,
and is a stimulus to our sensitivity that gives rise to the need,
to ask oneself at every opportunity the question how we should cultivate
the garden, which has been entrusted to us as a gift. Many Christians
have been enlightened of the fact that a more just handling of the
relationship between man and other living species may influence
judicial relations among men themselves.
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The
Theological Appeal
Theology points toward
educating us to see in the other animals not mere organic matter
at mans disposal but an organism living in relationships,
which man needs to understand fully before attempting to modify
them and manipulate their environments. Scientists are now attempting
to examine these ethical issues within the realm of experimentation.
If scientists continue to proceed in genetic testing without taking
into consideration the worth of other species then they will continue
to face opposition among many people.
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Researchers
and Their Scientific Process
For researchers who do
not consider the inhumane treatment of animals in the laboratory,
does this mean that they feel that other species dont matter?
We as human beings have the ability to morally decide between right
and wrong. Is causing pain to defenseless animals, for the sake
of scientific advancement a pervasiveness of sin? Is manipulating
the genetic make - up which God has given to each living creature
a sinful act?
Even though this tampering
of genes may prove to find more evidence in the causes of disease,
does this give a researcher the license to make life - changing
alterations in other species? Is there a higher good that out weighs,
the suffering mice and other animals undergo in the laboratory?
Can we assume that the suffering that they endure will enhance the
lives of humankind? Has humans placed themselves in the position
of being gods as was earlier stated?
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Are We Sinning?
Sometimes man does take
his intellect and work to extremes, to the point that it could be
viewed as sinful. Sin is always pervasive. Is testing of lower species
sinful in the sight of God. This living creature that God created
does it not have any rights to exist? These are questions that are
causing discussions among theology scholars and scientific researchers.
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Resurrection
and Redemption
Can we see any resurrection
and redemption in what science is uncovering for the sake of humankind
and other living creatures? Is the old adage No pain, gain
correct true in the scientific setting? Maybe, through these scientific
advancements some will say there is redemption through scientific
findings that will cure diseases like breast cancer, or Kaposis
sarcoma, and schizophrenia, where all living creatures can benefit.
Maybe, this can be viewed as resurrection and redemption.
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For Pastoral
Counselors
In light of disease and
their affect on humans, pastoral counselors can draw from the wealth
of resources and materials that discuss issues of disease, life
and death. They can use this material to point out that all living
creatures suffer, and encourage them to know that when one suffers
we all suffer. When we all suffer God suffers. In giving members
of ones congregation hope, pastoral counselors can help ill members
know that they do have options for receiving treatment of their
illness and they have science working to find the cures to all diseases.
Pastoral counselors must inform members who are struggling with
illness and disease to seek expert help for their treatment. Counselors
must also let them know that there is emotional support in their
church.
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Definitions
for this Discussion
Analogues
are likenesses found in humans and animals.
Collectively
means altogether.
Ethical
is a principle of right or wrong or good conduct.
Genetic coding
refers to the genetic make-up of humans and other species.
Genome
is the human gene make-up.
Individually
means each person.
Individuation
is the distinctiveness or uniqueness of an individual.
Interrelatedness
is to come into mutual relationship.
Living species
are animals other than humans.
Moral
means the judgment of the goodness or badness of human actions.
Retinal
atrophy concerns the wasting away of the inner lining of the eye.
Solidarity
is a togetherness or unity.
Transgenic
is moving of genes.
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Sources
http://www.wellcome.acuk/en/l/awtpregnmani.html
http://www.bmj.com/collections/bse/pridis.htm.
http://news.bbc.co.uk/hi/english/sci/tech/newsid_1112000/1112171.stm
Barker, Penelope - The Reference Shelf, The
H.W. Wilson Co., New York, 1995.
Birch, Bruce C., Rasmussen, Larry L., -
Bible and Ethics in Christian Life, Augsburg Fortress, Minneapolis,
Minnesota, 1989.
Jones, Gareth, D., -
Brave New People, William B. Eerdmans Publishing
Company, Grand Rapids, Michigan, 1984.
Mieth, Dietmar, Pohier, Jacques Concilium
Ethics in the Natural Sciences, T. & T. Clark Ltd., Edinburgh,
Scotland, 1989.
Nelson, Robert, J., -
Genetics and Religion, William B. Eerdmans Publishing Company,
Grand Rapids, Michigan, 1994.
Peters, Ted, -
Playing God?, Routledge, New York, 1997.
Ridley, Matt, -
Genome, Fourth Estate Limited, Great Britain, 1999.
Smith, Edward, Sapp, Walter, Plain
Talk about the Human Genome
Project, Tuskegee University, Tuskegee, Alabama, 1997.
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